| Sussex Curtain & Blind Company Ltd | Curtain maker and retailer | 29 Coombe Terrace, Lewes Rd | Mon–Fri 09:00–16:00 |
| Sussex Doors | Door supplier | 8-9, Centenary Industrial Estate, Hughes Rd | Sat 08:00–13:00 |
| Sussex Home Support | Social services organisation | 35b Providence Pl | Mon–Wed 10:00–16:00 |
| Sussex MSK Partnership Central | Medical group | 177 Preston Rd | Mon 09:00–17:00 |
| Sussex Print Management | Commercial printer | 31 Braybon Ave | Mon 09:00–17:00 |
| Sussex Rehabilitation Centre | Orthotics & prosthetics service | Sussex Rehabilitation Centre, Elm Grove | Mon–Fri 08:30–17:00 |
| Sussex Surveyors LLP | Surveyor | 22 Carlton Terrace | Fri 09:00–17:30 |
| Sustainable Gardening ltd | Gardener | 19 Over St | Daily Open 24 hours |
| Take Part in Research | Market researcher | 50 Grand Parade | Fri 09:00–17:30 |
| Target Five Property Consultants | Property investment | 2 Ashford Rd | Mon–Fri 08:30–18:00 |
| Telkev Telephone Broadband & Data Cable Engineers | Telecommunications engineer | 2 Whippingham St | Mon–Fri 08:00–17:00 |
| The Blackhouse Tattoo | Tattoo and piercing shop | 23 Clifton Hill | Daily 10:30–20:00 |
| The Book Marketer | Book publisher | Bevendean Cres | Mon–Fri 09:00–17:00 |
| The Dad Course | Childbirth class | 75 Barnett Rd | Daily Open 24 hours |
| The Doula Jo Slade | Doula | Fairfield Gardens | Mon–Fri 09:00–18:00 |
| The Edit | Video editing service | 96 Church St | Mon 09:00–18:00 |
| The Family Dental Practice | Dental clinic | 154 The Ridgway | Mon–Tue 09:00–17:00 |
| The Lanes Car Park | Car park | Black Lion St | Daily Open 24 hours |
| The Last Drip - Splatter Paint Studio | Art studio | 4 Brighton Square | Thu 11:00–20:00 |
| The Painting Pottery Cafe | Painting lessons | 31 North Rd | Thu 10:30–17:30 |
| The Private Press | Screen printer | Rodhus Studios, 16-30 Hollingdean Rd | Mon–Fri 09:30–17:30 |
| The Razors | Band | 160 Saunders Hill | Daily Open 24 hours |
| The Spice Shop | Spice shop | 10 Gardner St | Sat 10:00–18:00 |
| The Star Project - Sanctuary Supported Living | Assisted living residence | 36 Frederick Pl | Sun 08:00–20:00 |
| The Tone Rangers Choir | Choir | Church Rd | Wed 19:35–21:30 |
| Theme Works | Event management company | 15-17 Middle St | Mon–Fri 09:00–17:30 |
| Tidal Vape Shop Brighton | Vaporiser shop | 45 North St | Mon–Sat 09:00–19:00 |
| Tinkers Hardware | Hardware shop | 100 Dyke Rd | Mon–Fri 08:45–17:30 |
| Tint King Portslade | Window tinting service | 44 Harebell Dr | Sun 08:30–13:30 |
| Tom Way Drums | Drum school | 7 Trafalgar Arches | Mon–Fri 10:00–21:00 |