| Engage Computer Systems | Computer service | 12 Waggoners Dr | Thu 10:00–18:00 |
| Everheat - Heating and Renewables | HVAC contractor | Flat 3, 256 Salisbury Terrace | Daily Open 24 hours |
| Ewan Main - humanist celebrant | Marriage celebrant | St Helen's Rd | Mon 09:00–21:00 |
| Excel Sports Clinic - York | Sports injury clinic | 3, Cayley Court, George Cayley Dr | Thu 08:00–19:00 |
| Executive Hot Tub Hire North Yorkshire | Equipment rental agency | Unit C, Windmill Industrial Estate, Sutton Rd | Mon–Fri 10:00–16:00 |
| Express Electronics | Electronic parts supplier | 18 Kathryn Ave, Monks Cross Dr | Fri 08:00–16:30 |
| Fairways Garden Services | Fence contractor | 37 North Ln | Mon–Tue 08:30–17:30 |
| Fancy Hank's Bar & Kitchen | Hamburger restaurant | 39 Goodramgate | Mon 12:00–21:00 |
| Fenton Simpson Mortgage & Protection Specialists | Mortgage broker | York Biocentre, Innovation Way | Thu–Fri 09:00–17:00 |
| Findharmonycounselling | Counsellor | 15 Old Church Grn | Tue 09:00–19:00 |
| Fish and Forest | Seafood restaurant | 13 Grape Ln | Wed–Sat 10:00–23:00 |
| Flatout Moto | Second-hand motorcycle dealer | Unit 5, Poplar industrial estate | Fri 09:00–17:00 |
| FloCoe Interiors | Cabinet maker | FloCoe Interiors, Marcon Industrial Estate, Rice Ln | Mon 09:00–17:00 |
| Flowers by Joanna Keely | Florist | The Flower Studio, Cherry Garth, 50 Main St | Mon–Sat 09:30–16:30 |
| Ford York | Ford dealer | Monks Cross, Jockey Ln | Mon–Fri 08:30–18:00 |
| Fortus | Tax advisor | Equinox House, Clifton Park Ave, Shipton Rd | Mon–Fri 09:00–17:00 |
| Freckleface | Candle shop | 34 Shambles | Mon–Sat 10:00–18:00 |
| French Soaps UK | Cleaning products supplier | Unit 14, Ousegill Business Park, Carr Side Rd | Mon–Fri 08:00–18:00 |
| Fresh Medical Aesthetics & Skin Clinic | Nurse practitioner | Riccall Grange, 6 Milners Yard, King Rudding Ln | Mon–Fri 09:30–15:30 |
| Friars Hill Riding Stables | Horse riding school | Friars Hill | Mon–Fri 10:00–16:00 |
| Fruity and Frilly | Swimwear shop | 11 Stones Cl | Mon–Tue 09:00–17:00 |
| FULLY FLOORED carpet flooring and HOMEWARES SHOP | Carpet retail shop | 70-72 James St | Mon–Sat 10:00–17:00 |
| GB Auto-Care ltd | Used car dealer | Hirst Rd | Mon–Fri 08:30–17:00 |
| Genius IT Solutions (JKR Group Ltd) | IT support and services | 43a Shambles | Mon–Fri 09:00–17:00 |
| Get Branded Workwear & Schoolwear | Work clothes shop | 4 Unit 4 | Mon–Fri 08:00–17:00 |
| Glass Supplies York | Glass merchant | 50 Thief Ln | Mon–Fri 09:00–16:00 |
| Glasweld Systems UK Ltd | Glass repair service | Appletree Village, 92 Bramley Garth | Sat 08:00–20:00 |
| Goji Cafe | Vegetarian cafe and deli | 36 Goodramgate | Wed–Fri 11:00–16:00 |
| Graphics Direct Ltd | Art supply shop | Unit 16, Rudgate Business Park | Mon–Thu 08:00–17:00 |
| Gray and Vincent | Steel framework contractor | Coulson Park Farm | Mon–Tue 06:30–17:00 |