| Chris Taylor Gardening | Gardener | 21 The Cranbrooks | Daily 08:00–20:00 |
| Christine Alker Curtains and Blinds | Curtain maker and retailer | 5 Murray St | Mon–Tue 09:30–17:00 |
| City Cruises - Boat Tours (Lendal Bridge) | Tourist attraction | Lendal Bridge | Daily 08:00–20:00 |
| Clarity Office Solutions York | Printing equipment supplier | Regus Business Centre Tower Court, Oakdale Road, Clifton Moor Gate | Mon 08:30–17:00 |
| Clifford's Tower, York | Historical landmark | Tower St | Daily 10:00–17:00 |
| Clifton with Rawcliffe Primary School | Primary school | Eastholme Dr | Mon–Fri 08:30–15:45 |
| Coffee Spirit Co | Alcohol manufacturer | Harlequin Coffee House, 2b King's Sq | Sat 10:00–16:00 |
| Coleccion Alexandra UK | Furniture maker | 62 Gillygate | Mon–Fri 09:30–17:30 |
| Collier Plant Hire (York) Ltd | Plant and machinery hire | Station Yard, Temple Ln | Mon–Fri 07:00–17:00 |
| Communicate | Internet service provider | 3 Innovation Cl | Mon–Fri 09:00–17:00 |
| Computer Science IT Support | Computer consultant | Department of Computer Science, University of York, Deramore Ln | Thu 09:00–17:00 |
| Cooltec Services (York) Ltd | Air conditioning contractor | 4 B Chessingham Park, Common Rd | Mon 09:00–05:00 |
| Cooper King Distillery | Distillery | The Old Stable, Stillington Rd | Wed 14:30–17:00 |
| Copmanthorpe Mots | MOT centre | Main Street, Main St | Mon–Tue 08:30–17:00 |
| Coppergate Clinic | Plastic surgery clinic | Coppergate Clinic |, 8 Coppergate | Mon–Thu 09:00–18:30 |
| Core Chiropractic | Chiropractor | 121 Nunnery Ln | Mon 10:00–19:00 |
| Corner Gallery | Art studio | 2 Telford Terrace | Fri 11:00–18:00 |
| Corner Grill House | Steak house | 12a King St | Mon–Fri 16:30–22:00 |
| Corner Studio, York | Art school | Alma | Thu 10:00–02:30 |
| Corries Solicitors | Personal injury lawyer | 11, Melroses Yard, Walmgate | Mon–Fri 09:00–17:00 |
| Craft Burger York | Hamburger restaurant | 85 Clarence St | Daily 12:00–23:00 |
| Creative AV Solutions LTD York | Security system installation service | 36 Rosebery St | Daily Open 24 hours |
| Crescent Architects Ltd | General contractor | 6 The Crescent | Mon–Fri 09:00–17:00 |
| Crossroads Truck & Bus | Truck dealer | Unit 1, Crossroads Business Park, Bar Ln | Mon–Fri 07:00–22:00 |
| D & J Stead Contracting | Agricultural service | Claremont House | Mon–Fri 08:00–17:30 |
| Dancing Goat Coffee Ltd | Coffee machine supplier | Unit 5, Centre Park, Marston Moor Business Park | Mon–Fri 09:00–17:00 |
| David Dale Removals | Removals company | Unit 3, Langby Industrial Estate, Milby Gdns | Mon–Thu 09:00–17:00 |
| David Tompkins Ltd - Fibre Cement York | Roofing service | Church Farm | Mon–Fri 08:00–17:00 |
| Dawnay Farm Christmas Trees | Seasonal goods shop | The Old Barn | Daily 10:00–16:00 |
| Day Lewis Pharmacy York. Badger Hill | Pharmacy | T/A: Badger Hill Pharmacy). 35 Yarburgh Way Badger Hill | Mon–Fri 09:00–18:00 |