| Cherry Tree | Bar & grill | 35 Common Ln | Mon 12:00–22:00 |
| Cheshire back pain clinic | Pain control clinic | NEWSPAPER HOUSE, Tannery Ln | Mon–Wed 10:00–19:00 |
| Cheshire Brush | Signwriting service | 33 Runnymede | Mon 09:00–21:00 |
| Cheshire CBT | Psychotherapist | Cheshire Natural Health Beehive House, Tarporley Rd | Wed 08:30–17:00 |
| Cheshire Clinical Contour Treatments and training. | Training centre | 53 Church St | Mon–Sat 11:00–18:00 |
| Cheshire Cycles | Bicycle repair shop | Unit 3 A, The Old, The Heliport, Appleton Thorn Ind Est, Lyncastle Rd | Mon–Fri 09:00–18:00 |
| Cheshire Electrolysis | Electrolysis hair removal service | Cheshire Beauty and Wellbeing, Old Alder Ln | Tue 12:00–20:00 |
| Cheshire Exterior Cleaning & Pressure Washing Services | Pressure washing service | 10 Victoria Rd | Thu–Fri Open 24 hours |
| Cheshire Gold Xchange | Gold dealer | 3 London Rd | Mon–Fri 10:00–17:00 |
| Cheshire House Moves | Removals company | Unit E4, Trident Industrial Estate, Warrington Rd | Mon–Fri 08:00–17:00 |
| Cheshire Minibus Hire | Coach and minibus hire | Business Park, Unit B Catherine St | Daily Open 24 hours |
| Cheshire Natural Health | Holistic medicine practitioner | Beehive House, Tarporley Rd | Thu 09:00–20:00 |
| Cheshire Pressure | Pressure washing service | 4 Susan Dr | Daily 07:00–20:00 |
| Cheshire Vehicle Supplies | Motor vehicle dealer | 1 New Cut Ln | Mon–Thu 09:00–17:00 |
| Chimney Pro | Chimney sweep | 1 Herbert St | Mon–Sat 08:00–20:00 |
| China Red | Chinese restaurant | 76 Mersey St | Mon–Tue 16:00–23:00 |
| Chinese Alternative Medical Centre | Alternative medicine practitioner | 6 Dundonald Ave | Mon–Fri 09:00–20:00 |
| Citibase Warrington Birchwood | Business centre | Genesis Centre, Garrett Fld | Thu–Fri Open 24 hours |
| Cjl Flatpack Assembly | Handyman/Handywoman/Handyperson | St Mawgan Ct | Daily Open 24 hours |
| ClearComms Group Limited | Telecommunications contractor | 15 Springfield St | Mon–Thu 08:30–17:30 |
| Clearview Home Improvements | Window installation service | Unit 6, Gemini Trade Park, Europa Blvd | Mon 09:00–17:30 |
| Code It Labels Ltd | Commercial printer | 21 Trinity Ct | Mon–Fri 08:30–17:15 |
| Community Recycling Centre | Household waste recycling centre | Sandy Ln | Daily 10:00–16:00 |
| Concept Commercial Interiors Ltd | Office refurbishment service | Birchwood Park | Mon–Thu 09:00–17:00 |
| Concord Plumbing & Heating | Plumber | Sandfield Cres | Mon–Fri 08:00–16:00 |
| Cordis | Medical equipment manufacturer | Cordis Medical UK Limited, Chadwick House Warrington Rd | Mon–Fri 09:00–17:00 |
| Cosmetic Couture Culcheth | Cosmetics industry | 60 Lodge Dr | Mon–Wed 10:00–18:00 |
| Cosmetic Treatments and Injectables Academy (CTIA Training) | Training centre | Old Alder Ln | Mon–Fri 09:00–17:00 |
| Cottam Parkinson Consulting Ltd | Consultant | 27 Lasky Ln | Mon–Fri 08:00–18:00 |
| CQ Catering | Caterer | Highcroft Barn, Lady Ln | Mon–Thu 07:00–18:00 |