| Guardi Southwest | Security service | Unit 5, 62 Valley Rd | Daily Open 24 hours |
| H & H Healthcare Limited | Social services organisation | 2, Langage Business Park, 1 Eagle Rd | Mon–Fri 08:00–16:00 |
| H.M. Williams Chartered Certified Accountants | Bookkeeping service | Langage Business Park, 5 Sandy Court, Ashleigh Way | Mon–Thu 09:00–17:00 |
| Hackworthy and Sons Removals | Removals service | The Depository, Elliott Rd | Mon 09:00–17:30 |
| Hadley Engineering Group | Metal fabricator | 1 Parkwood Cl | Mon–Fri 07:30–16:00 |
| Hair Solutions | Hair replacement service | Unit 1, Eurotech Park, Burrington Way | Tue–Wed 09:00–17:00 |
| Hamoaze House | Addiction rehabilitation centre | George Street, Mount Wise | Mon–Fri 09:00–17:00 |
| Handyman Fit and Fix | Handyman/Handywoman/Handyperson | 25 Glenhurst Rd | Mon–Fri 08:30–17:30 |
| Harris Hounds | Dog walker | 19 Sharrose Rd | Mon–Fri 09:00–17:00 |
| HBH Woolacotts (Plymouth) | Electronics retail and repair shop | 71 Coypool Rd | Thu 09:30–18:00 |
| Hedsite Press | Book publisher | Hedsite Press, 74 Furzehatt Rd | Mon–Fri 09:00–17:00 |
| Heritage Upholstery | Upholstery shop | Carfrae House, 74 Ladysmith Rd | Mon–Fri 09:00–17:00 |
| Hire Class | Marquee hire service | Wolverwood Farm, Wolverwood Lane | Mon–Fri 08:30–16:30 |
| Hockin Gold Ltd | Commercial property estate agent | Brownston, Plymouth PL8 2JB | Mon 09:00–18:00 |
| Holistic Beatz | Reflexologist | Unit 4, Lynher House, Bush Park | Mon 09:30–17:00 |
| HomeSupply Retail Ltd | Bathroom supply shop | 8-10 Faraday Rd | Mon–Fri 09:00–17:00 |
| Horseman Groundworks | Landscaper | 1 Sunderland & Spencer Cottages | Mon–Sat Open 24 hours |
| Hospitality Plymouth | Catering food and drink supplier | 95 N Rd E | Thu 08:00–17:00 |
| Hot Diggity Dog | Dessert shop | N Prospect Rd | Mon–Tue 16:30–22:00 |
| Hot Slots Casino | Amusement centre | Unit 11 The Broadway | Mon–Thu 09:00–22:00 |
| House To Home | Building restoration service | Strode Rd | Mon–Fri 09:00–17:00 |
| HS Interiors ltd | Kitchen furniture shop | Unit 8-10 Faraday Mill Business Park, Faraday Rd | Mon–Fri 09:00–17:00 |
| Huddle Content Studio | Video production service | Candlwick Lane, 6 Alma Yard | Mon–Sat 09:00–17:00 |
| Hybrid Combat Gym | Martial arts school | Hybrid Gym, Clare Pl | Mon–Fri 06:30–10:30, 17:00–21:00 |
| Impact Flags | Flag shop | 5 Cross Park Rd | Mon–Fri 09:00–17:00 |
| Imperial Garden | Chinese restaurant | 45 Ebrington St | Mon–Tue 17:00–23:30 |
| inacoustic | Acoustical consultant | Plymouth Science Park, 1 Davy Rd | Mon–Fri 09:00–17:30 |
| Infinite Surface Repairs Ltd | Repair service | 2 Stanbury Ave | Daily Open 24 hours |
| Insero Therapy | EMDR psychotherapist | 34 Mannamead Rd | Mon 09:00–17:00 |
| Interseal South West Ltd | Window installation service | Unit 8, Alder Court, Bell Cl | Mon 08:30–17:00 |