| F.H.Crocker & Co | Dry wall contractor | 14 Crozier Rd | Mon–Fri 08:00–17:00 |
| F3 Design Wedding & Event Stationery | Wedding service | 2 Orchard Cres | Mon–Fri 09:00–16:00 |
| Falcon Properties | Estate agent | 8 Mannamead Rd | Mon–Fri 09:00–17:30 |
| Faye Channing | Health counselor | The Dragonfly Wellbeing Centre, 34 Mannamead Rd | Mon–Thu 19:00–21:00 |
| Fire Door Installers Plymouth & South West | MJC Passive Fire Ltd | Fire protection service | Unit 16, Wolseley trust Business Park, Wolseley Cl | Mon–Fri 09:00–16:00 |
| First Care Ambulance (Plymouth Base) | Ambulance service | 55 Drake Mills Business Park, Estover Rd | Daily Open 24 hours |
| First Light | Domestic abuse treatment centre | 2 Cattedown Rd | Mon–Fri 09:00–17:00 |
| Flameworks Creative Arts Facility | Art studio | 7 Richmond Walk | Daily 10:00–21:00 |
| Fletewood School | Independent school | 88 N Rd E | Mon–Fri 08:00–17:00 |
| Flexihose | Hose supplier | 16 Miller Ct | Mon–Thu 08:00–16:30 |
| Floor Sanding Plymouth | Floor sanding and polishing service | George Pl | Mon–Fri 09:00–17:30 |
| Flourish Psychology | Psychologist | 2 Cattedown Rd | Mon–Fri 09:00–17:00 |
| Flying Start @ Marjon | Day care center | Parking lot, Marjon College, Derriford Road | Mon–Fri 07:30–18:00 |
| Fone World | Mobile phone repair shop | 5 New George St | Mon–Sat 09:00–18:00 |
| Foot Solutions | Orthopaedic shoe shop | 34 Royal Parade | Mon–Sat 09:30–17:00 |
| Four Elements Catering | Caterer | 17 S Milton St | Daily Open 24 hours |
| Fresh Air Studios | Advertising agency | 2, Russell Court, Ground Floor Studios, St Andrew St | Mon 08:30–18:00 |
| Fringes | Rug shop | Unit A/C Strode Road Newnham Industrial Estate | Mon–Sat 09:00–17:00 |
| Fuel Communications | Marketing consultant | 9 The Crescent | Mon–Fri 08:00–18:00 |
| Fulfords Estate Agents Plymouth St Budeaux | Estate agent | 2 Pemros Rd | Mon–Fri 09:00–17:30 |
| Furniture World Plymouth | Home furniture shop | Unit 3, Coypool Retail Park, Coypool Rd | Mon–Sat 09:00–17:30 |
| Future Image Studios | Photography studio | 6 Mary Seacole Rd | Daily 08:00–22:00 |
| Gables Dogs & Cats Home | Animal shelter | 204 Merafield Rd | Mon–Fri 09:00–16:00 |
| Galaxy Nails | Beauty supply store | 17, Faraday Mill, Business Park | Thu 08:30–16:00 |
| Gas Jack Group Limited | Commercial agent | 1, Officers Quarters, Crownhill Fort, Crownhill Fort Rd | Fri 08:00–17:00 |
| George Rosenberg Immigration Law | Immigration lawyer | 10 The Square | Mon–Fri 09:00–17:00 |
| Grace Osteopathy & Wellness Clinic, Plympton | Osteopath | Colebrook, 12 Colebrook Rd | Mon–Fri 09:00–19:00 |
| Green Tree Holistic Therapy | Hypnotherapy service | Unit 4, Lynher House, 3 Bush Park | Tue–Sat 16:00–20:00 |
| Greenlight Safety and Training (Head Office) | Training provider | Bergstrand House Parkwood Close | Mon 08:00–17:00 |
| GT Motorcycles | Motorbike dealer | 10-12 Elburton Rd | Mon–Sat 09:00–17:30 |