| Children 1st Mediation Plymouth + Online Uk wide | Mediation service | Unit 3, 21 Phoenix St | Mon–Fri 09:00–17:00 |
| Church of Scientology of Plymouth | Religious organisation | 41 Ebrington St | Mon–Fri 09:00–22:00 |
| City Furnishers | Bedroom furniture store | Colin Campbell House, Colin Campbell Court Carpark | Mon–Sat 09:00–17:00 |
| ClayArt | Painting studio | 57 Southside St | Thu 10:00–17:00 |
| Clean Thru | Pressure washing service | 1 leatside | Mon–Sat 08:00–17:00 |
| Cleaner Cleaners | House cleaning service | 4 Kemyell Place | Mon–Sat 07:00–19:00 |
| Cleanspares Plymouth Ltd | Scrap yard | 64a Valley Rd | Mon–Fri 07:30–17:00 |
| Clippers and Cliphers | Barber shop | 73 The Ridgeway, Ridgeway | Mon–Sat 09:00–17:00 |
| Club Continental | Fitness centre | Millbay Rd | Mon–Fri 07:00–21:00 |
| Cobblers and Coffee | Key duplication service | 117 Beaumont Rd | Mon–Thu 08:00–16:00 |
| COFAST Ltd | Fastener supplier | 41 Valley Rd | Mon–Thu 07:30–16:30 |
| Colour Drench Studio | Painting studio | Unit 61-62, Industrial Estate, Christian Mill Business Park, Tamerton Foliot Rd | Thu 10:00–14:00 |
| Commercial Mortgages UK | Mortgage lender | 6 Keppel Pl | Mon–Tue 09:00–17:00 |
| Community in print | Arts organisation | Mutley Rd | Mon–Sat 10:00–16:00 |
| Complete Business Solutions | Office equipment supplier | Unit 3, Drakes Court Eagle Rd, Langage Business Park | Mon–Thu 09:00–17:00 |
| Considered Solutions Ltd | Fire protection consultant | 138 Dudley Rd | Mon–Fri 08:00–17:00 |
| Continuum (Financial Services) LLP | Insurance agency | Eagle Rd | Mon–Fri 09:00–17:00 |
| Cor-Heat Plumbing And Heating Ltd | Gas engineer | Unit 4, Seaton Park, 36 William Prance Rd | Daily Open 24 hours |
| Cornwall Glass Manufacturing Ltd | Commercial and Trade Customers only | Glass manufacturer | 3 Beechwood Way | Thu 08:00–17:00 |
| Coronet Engravers | Engraver | 16 Market Stalls | Mon–Sat 09:30–16:30 |
| County Fasteners Ltd | Wholesaler | Unit 33, Faraday Mill, business park | Mon 07:30–16:30 |
| Crownhill Conservatories Ltd | Conservatory contractor | Fort Austin Ave | Mon–Sat 09:00–16:30 |
| Custom Boat Upholstery | Upholstery shop | Blagdons Boatyard, Richmond Walk Devonport | Mon 08:00–17:00 |
| Custom House Plymouth - Events & Wedding Venue | Events venue | Custom House (left entrance | Fri 17:00–01:00 |
| Cut & Clear gardening services | Gardener | 24 Efford Rd | Daily Open 24 hours |
| Dartmoor Zoo | Tourist attraction | Plymouth PL7 5DG, United Kingdom | Daily 10:00–16:00 |
| DCA PR | Public relations firm | Unit 10 Cargo, 37 George Pl | Mon–Fri 08:30–17:00 |
| Delta Engineering | Machinery parts manufacturer | Darklake View | Mon–Fri 08:00–16:30 |
| DentalCarePlus Dental Implant Centre | Dental implants periodontist | Logic House, Transit Way, Crownhill Rd | Mon–Fri 09:00–17:00 |
| Derriford Church | Church | Derriford United Reformed Church, Powisland Dr | Sun 10:30–12:00 |