| Clearwell Mobility | Mobility equipment supplier | 106-110 Warren Rd | Mon–Sat 09:00–17:00 |
| Click Clean Clothes | Dry cleaner | 39-40 Coombe Terrace | Mon–Fri 10:00–15:00 |
| Clive Emson Land & Property Auctioneers Sussex and Surrey | Auction house | 83 Bates Rd | Mon–Fri 09:00–17:30 |
| Cloth Control | Fabric shop | 6a Kensington Gardens | Mon–Sat 10:00–18:00 |
| Cmk Planning | Urban planning department | 11 Jew St | Mon 09:00–17:00 |
| Coastway Vets, Brighton | Veterinary pharmacy | Freshfield Industrial Estate, Stevenson Rd | Daily Open 24 hours |
| College Of Classical Massage | Massage school | 20-26 Round Hill St | Sat–Sun 09:00–21:00 |
| Commercial Catering Contracts Ltd | Catering supplier | Waterside House | Mon–Fri 08:30–17:00 |
| Community Transport (Brighton, Hove and area) Ltd | Non-profit organisation | Protran House, 5859 Boundary Rd | Tue 09:00–17:00 |
| Concorde 2 | Live music venue | 286A Madeira Dr | Mon–Thu 19:00–23:00 |
| Constantinople Restaurant | Turkish restaurant | 51 Norfolk Square | Daily 12:30–22:00 |
| County Oak Medical Centre | Public medical centre | County Oak Medical Centre, Carden Hill | Thu 08:30–13:00 |
| Couplestherapybrighton.co.uk | Marriage counsellor | 160 Church Rd | Mon–Fri 09:00–20:00 |
| Covers Timber and Builders Merchants - Brighton | Timber merchant | Home Farm Business Centre | Thu 07:00–17:00 |
| Cre8 Zero Ltd | Solar energy company | 83 Queens Rd | Mon–Fri 09:00–18:00 |
| Create Music | Music school | Pelham Terrace, now Create Music Sound Rooms, 3, Lewes Rd | Mon–Fri 09:00–17:00 |
| Crunch & Co | Sandwich shop | 7 Church St | Mon–Sat 11:00–17:00 |
| Cryptosussex | Financial advisor | Drove Rd | Mon–Thu 09:00–20:00 |
| CSnotepad | Telephone answering service | The Offices, 57 Newtown Rd | Mon–Fri 08:30–18:00 |
| Cub Animation Studio | Animation studio | Metal Works, 4-5 Gloucester St | Mon–Fri 09:30–18:00 |
| Cunningtons LLP Solicitors Brighton | Law firm | 31 Duke St | Mon–Fri 09:00–17:30 |
| Cyan Brighton | Modern British restaurant | The Grand, 97-99 Kings Rd | Mon–Sat 17:00–21:30 |
| D.R. Computer Repairs | Computer service | 14 Anvil Cl | Mon–Fri 08:00–19:00 |
| Dave's Comics | Comic book shop | 3 and 5 Sydney St | Mon 10:00–18:00 |
| Dean Wood Care Home - Bupa | Nursing home | Warren Rd | Daily Open 24 hours |
| Demolition Paintball - Brighton | Paintball centre | Centre, Kings Rd | Daily 09:00–17:00 |
| Diamond Glass and Windows Ltd | Glass merchant | 8-9, Centenary Industrial Estate, Hughes Rd | Mon 08:00–17:00 |
| Dice Saloon | Board game club | 88 London Rd | Mon 12:00–19:00 |
| Dietitian By The Sea | Dietitian | 83 Queens Rd | Mon–Fri 09:00–17:00 |
| Dinnages Ford Brighton | Ford dealer | Victoria Rd | Thu 07:00–18:00 |