| Sushi Garden | Japanese restaurant | 32A Preston St | Mon–Fri 12:00–15:00, 17:30–22:30 |
| Sussex Aluminium Systems | Aluminium frames supplier | Unit 9, Centenary Industrial Estate, Hughes Rd | Mon 08:30–17:00 |
| Sussex Banners | Banner shop | 2, 4 Foredown Dr | Mon–Fri 08:30–17:00 |
| Sussex Blinds & Shutters | Blinds shop | 36-38 Warren Rd | Mon–Fri 09:00–17:00 |
| Sussex Clothing | Clothing supplier | 2, 4 Foredown Dr | Mon–Tue 08:30–17:00 |
| Sussex Community NHS Trust | Hospital | Elm Grove | Mon–Fri 08:00–16:00 |
| Sussex Emmaus | Charity shop | Drove Rd | Tue 09:30–17:00 |
| Sussex Foot & Ankle Clinic | Orthopaedic surgeon | Nuffield Hospital, Warren Rd | Thu 08:00–20:00 |
| Sussex Gourmand | Gift shop | 100 Church St | Daily Open 24 hours |
| Sussex harpist - Magdalena Reising | Musician and composer | Marine Gate | Daily Open 24 hours |
| Sussex Implant Centre and Advanced Dentistry | Dental clinic | Woodingdean Hazel Cottage | Mon–Thu 09:00–18:00 |
| Sussex Kidney Unit | Hospital department | Eastern Rd | Mon–Fri 08:00–17:00 |
| Sussex Local Wine School | Wine club | Hotel du Vin Brighton, 2 Ship St | Sat 11:00–16:00 |
| Sussex Teachers | Educational consultant | Floor 8, Tower Point, Platform 9, 44 North Rd | Mon–Fri 07:00–19:00 |
| Sussex Wildlife Trust | Non-profit organisation | First Floor, The Keep, Woollards Wy | Mon–Fri 09:00–16:00 |
| Swim Skills School | Swimming school | 3 Sunnydale Ave | Wed–Fri 15:30–18:30 |
| Taboo | Shop | 2 Surrey St | Mon–Fri 10:00–18:00 |
| Tailored Tutors | Tutor | 6 Wykeham Terrace | Mon–Fri 09:00–19:00 |
| Tamarind | Thai restaurant | 65 Preston St | Mon–Fri 12:00–15:00, 17:00–22:00 |
| Tarnerland After School and Holiday Club | After-school programme | Tarner Park, Sussex St | Daily 17:00–20:00 |
| Tarot by the sea | Clairvoyant | Cannon Pl | Mon–Sat 09:30–20:30 |
| Tates - Citroën Brighton | Citroen dealer | 138 -166 Trafalgar Rd | Mon–Sat 08:00–18:00 |
| Tates - Fiat Brighton | Vehicle repair shop | 138-166 Trafalgar Rd | Mon–Fri 08:00–18:00 |
| Taylors Tobacconists | Cigar shop | 19 Bond St | Mon–Fri 10:00–17:30 |
| TechNative Digital | Software training institute | Plus X Innovation Brighton, Lewes Rd | Mon–Fri 09:00–17:00 |
| Technozen Electronics | Electronic engineering service | 44 Meadow View | Mon–Fri 09:00–17:30 |
| TECO Building Products | Building materials market | Wellington Rd | Mon–Thu 07:00–16:30 |
| Ted Langley Ltd | Wholesale florist | Unit 4, Crowhurst Corner, 7 Crowhurst Rd | Mon–Sat 07:00–09:30 |
| Ten Green Bottles Brighton Wine Bar and Shop | Wine shop | 9 Jubilee St | Mon 16:00–22:00 |
| terre à terre | Vegetarian restaurant | 71 East St | Mon 17:00–22:30 |