| St Thomas Centre | Religious destination | St Thomas Centre, 1 Semilong Rd | Mon–Fri 08:00–20:00 |
| St. John's Multi Storey Car Park | Car park | Swan St | Daily Open 24 hours |
| Starlite Limos | Wedding planner | Unit A Tweed Rd | Daily 10:00–22:00 |
| Steamngo Valeting and Detailing Service | Valeting service | 19A Cotton End | Mon–Fri 08:00–18:00 |
| Step 'n' Pump - Please Call To Make Appointment | Sportswear shop | Warehouse. , 4 Carousel Way | Daily 08:30–21:30 |
| Steve Dodds - Utility Warehouse | Electric utility company | Churchill Rd | Mon 08:00–18:00 |
| Stonor Medical Limited | Recruiter | Ste 4, Main Rd | Daily Open 24 hours |
| SUGARPOLE Dance & Aerial | Dance school | First Floor, 32 Connaught St | Mon 18:00–22:00 |
| SunSushi | Sushi takeaway | 75 St Leonards Rd | Tue–Sun 14:00–21:00 |
| Super Sausage Cafeteria | Cafe | Watling St, A5 | Mon–Thu 07:30–14:30 |
| Sytner Land Rover Northampton | Land rover dealer | Swan Valley Way | Mon–Fri 08:00–18:00 |
| Sywell Country Park | Country park | Park View, 13 Washbrook Ln | Daily Open 24 hours |
| Tasty chicken!! | Chicken restaurant | 174 Kettering Rd | Mon 12:00–23:00 |
| Taylors Garden Buildings | Garden building supplier | A43, Woodmeadow Garden Centre, Kettering Road | Mon–Sat 09:00–17:00 |
| TBV Axemasters Northants | Adventure sports centre | Unit 11, The Stores | Tue–Sat 11:00–21:00 |
| The Cabin of Curiosity | Gift shop | unit 10, Billing Garden Village, The Causeway | Wed–Sat 09:30–16:00 |
| The Dining Room | Restaurant | 82 Derngate | Tue–Sun 10:00–16:30 |
| The Gorilla | Bar | 227 Wellingborough Rd | Thu 17:00–22:00 |
| The Green Coffin Company Ltd | Coffin supplier | Guilsborough Hill | Daily Open 24 hours |
| The Jungle @ Bips | Bar & grill | Ecton Brook Rd | Tue–Fri 17:00–22:30 |
| The Modern Balloon Company | Balloon artist | 19 Cripps Rd | Mon–Fri 10:00–17:00 |
| The Railway Conductor Ltd | Model train shop | Unit 2 The Old Dairy Farm Craft Centre | Mon–Sat 09:30–16:30 |
| The Reading Tree | Book shop | Building 1, The Depot | Daily 10:00–16:00 |
| The Squirrels | Restaurant | 31-33 Main Rd | Mon–Thu 12:00–23:00 |
| The Tearoom At Woodmeadow | Tea room | Woodmeadow Garden Centre, A43 | Mon–Fri 10:00–15:00 |
| The White Swan, Holcot | Pub | Main St | Mon–Tue 16:00–21:00 |
| The Window Cleaning Company | Pressure washing service | 67 Osmund Dr | Daily Open 24 hours |
| Through the Woods Counselling Ltd | Psychotherapist | Stoke Rd | Mon–Sat 07:30–20:00 |
| Timber Tech Tree Services LTD | Arborist service | 39 Brington Rd | Daily 07:30–17:00 |
| Tower Farm Saddlers | Saddlery | 3 King St | Mon–Sat 09:30–18:00 |