| Cotswold BMW Motorrad Cheltenham | BMW motorcycle dealer | 2, Corinthian Park, Corinthian Wy | Mon–Fri 08:00–18:00 |
| Cotswold Cheltenham MINI | MINI dealer | Corinthian Park, Corinthian Wy | Mon 08:00–18:00 |
| Cotswold Conservatories | Conservatory contractor | Unit 4, Burley Fields Lake, Leckhampton Ln | Mon–Tue 08:00–16:30 |
| Cotswold Custom Clothing | Work clothes shop | Unit 19, Old Station Yard Business Park | Mon–Fri 08:00–16:00 |
| Cotswold Hill Stone & Masonry Ltd | Stone supplier | Cotswold Hill Quarry, Ford | Fri 07:30–16:00 |
| Cotswold Home Improvement Supercentre | Window supplier | Unit 3, Beech Court, Bourton Industrial Estate | Mon–Tue 07:30–17:00 |
| Cotswold Motoring Museum & Toy Collection | Museum | The Old Mill, Sherborne St | Fri–Sat 10:00–18:00 |
| Cotswold Sandblasting Services Ltd | Blast cleaning service | Unit 20, Old station, Yard Business Centre, Station Rd | Mon–Sat 07:00–19:00 |
| Cotswold Trailers Ltd | Trailer supply shop | Woodside, Stow Rd | Mon–Fri 08:00–17:00 |
| Cotswold Van Centre Ltd | Truck dealer | Shurdington Rd | Mon–Fri 08:30–17:30 |
| Cotswold Vet Physio | Rehabilitation centre | Freedom House, 2 Rutherford Way | Mon–Fri 08:00–20:00 |
| Cotswold Wedding Co | Wedding service | Unit 17, CHELTENHAM TRADE PARK | Fri 10:00–15:30 |
| Cotswolds Restoration Services | Antique furniture restoration service | Stanway Grounds Broadway Road | Mon–Fri 08:00–17:30 |
| County Drain Services Your independent family run drainage specialist | Drainage service | 36 Kingsmead Rd | Mon–Thu 09:00–22:00 |
| Create and Bloom Crafts | Arts and crafts shop | Room 2, Unit 20D, Bourton Industrial Park, Hacklings House | Wed 09:00–14:45 |
| Curtain Call | Curtain shop | 134 Brooklyn Gardens | Mon–Fri 08:00–17:30 |
| Cyber 139 | Internet marketing service | 24 Charlton Dr | Mon–Fri 08:30–18:00 |
| Cygnus Music Ltd | Music management and promotion | 4 Imperial Square | Mon–Thu 09:00–17:00 |
| DDV Smart Solutions ltd | Car body shop | Kingsditch Trade Park, R1, Kingsville Rd | Mon–Thu 09:00–18:00 |
| Debt Recovery | Debt collection agency | Hollis House, The Square, Market Square | Daily 09:00–17:00 |
| Deep Dive Cleaners Ltd | Carpet cleaning service | St George's St | Mon–Fri 08:00–18:00 |
| Deepam South Indian Restaurant | South Indian restaurant | 56 High St | Sun 16:00–23:00 |
| Derek Taylor Roofing & Exterior Painting | Roofing service | Branch Cottage, Branch Rd | Fri 09:00–17:00 |
| Digital Scales Company | Scale supplier | Units A6-A7, Withytree Farm, Broadway Road | Mon–Fri 09:00–17:00 |
| DJ Coulter & Associates, Chartered Certified Accountants | Tax advisor | 7 Clarence Parade | Mon–Fri 09:00–17:30 |
| DMW Administrative Services | Business administration service | Little Shurdington, Shurdington, Cheltenham GL51 4TY | Mon–Sat 09:00–20:00 |
| Don Browning Trophies | Engraver | 4 St George's St | Mon–Tue 09:00–17:00 |
| Dprachi Beauty | African goods shop | 37 Winchcombe St | Mon–Fri 09:00–18:00 |
| Dream Feeds Ltd | Lactation service | 32 Wellington Rd | Mon–Fri 10:00–15:00 |
| Dunkertons Park | Events venue | Dowdeswell Park, The Barlands, London Rd | Mon 08:00–23:00 |