| DW Accountancy | Tax advisor | The Crescent | Daily Open 24 hours |
| Dynamic Customs | Car body shop | 105 Halliwell Rd | Mon–Sat 09:00–18:00 |
| Earful - Ear Wax Removal & Hearing Tests | Hearing aid shop | Earful, 29-31 Knowsley St | Mon–Wed 09:00–18:00 |
| Earl's | Day & Night Deli | Bolton | Deli | 621 Chorley Old Rd | Tue–Wed 08:00–16:00 |
| Eaststone | Pharmaceutical company | Unit 1 Barrs Fold Rd | Mon–Fri 09:00–19:00 |
| Eckersley's Removals | Removals company | 7 Smith's Rd | Mon–Sat 08:00–20:00 |
| Eckersleys Plumbers & Locksmiths | Plumber | 29 Central Ave | Daily 08:00–20:00 |
| Egerton Business Centre | Business centre | The Old Mill House, Deakins Business Park | Fri 09:00–17:00 |
| Eleva Cleans | House cleaning service | Westgate House, Westgate Ave | Mon–Fri 08:00–18:00 |
| Elite Boxing | Boxing club | B, Wordsworth Mill, Wordsworth St | Mon–Thu 07:00–21:00 |
| Empire Business Support Ltd | Bookkeeping service | 96 Chorley New Rd | Mon–Fri 09:00–17:00 |
| ENdynamics Mobility and Rehab | Mobility equipment supplier | 1 Gladstone Court, Egerton St | Mon–Fri 10:00–14:30 |
| Enhance Clinispa Skin Clinic | Medical spa | 353 Park Rd | Tue 09:00–18:00 |
| Etl Global Uk | Tax advisor | 1, Pavilion Square, Cricketers Way | Mon 09:00–17:00 |
| Etron (UK) Limited | Door supplier | Unit 6A, Meadow Business Park, Meadow Ln | Daily Open 24 hours |
| events4 | Wedding planner | 75-77 Market St | Mon Open 24 hours |
| Exceed Events | Weddings | Corporate | AV Hire | Event planning service | Unit 8, The Mill, 29 Bury New Rd | Tue 09:00–17:00 |
| Family Law Lawyer Manchester | Family lawyer | Hamill House, 112-116 Chorley New Rd | Mon–Fri 09:00–17:00 |
| Farnworth & Kearsley Labour Club | Club | 1K Long Causeway | Mon 18:00–23:00 |
| Farnworth Baptist Church | Baptist church | The Well, Trafford St | Mon–Wed 10:00–14:00 |
| Farnworth Carpets | Flooring shop | 53-55 Long Causeway | Mon 10:00–16:00 |
| Farnworth Leisure Centre | Leisure centre | 136 Brackley St | Mon 06:30–21:30 |
| Farnworth Mot Station | MOT centre | Whoolden St | Mon–Fri 07:00–17:00 |
| Farnworth Slimming World with Louise | Weight-loss service | Farnworth Baptist Church, Trafford St | Sat 07:30–08:45, 09:00–10:15, 10:30–11:45 |
| Feet First Podiatry and nail surgery Bolton | Chiropodist | 677 Chorley Old Rd | Fri 08:30–18:30 |
| First Step Vehicle Solutions - Van Leasing | Van rental agency | Unit F Lecturers Cl | Mon–Fri 09:00–17:30 |
| Fletcher CRE | Surveyor | Halcyon House, 20 Chorley New Rd | Mon–Fri 09:00–17:00 |
| Fletchers Solicitors | Personal injury lawyer | 1B, The Parklands | Mon–Fri 08:00–19:00 |
| Fourgates Flooring | Flooring shop | Fourgates Mill, Chorley Rd | Mon–Fri 09:00–17:00 |
| Frasers Butchers Ltd | Butchers | 272 Rishton Ln | Mon–Tue 08:00–17:00 |