| Noodle Lane 米巷 | Chinese restaurant | 74 Walmgate | Daily 12:00–21:30 |
| Oceans Fish and Chips | Fish and chips takeaway | 22 Eastholme Dr | Mon 16:00–21:00 |
| Orion Windows | Conservatory contractor | Clifton Industrial Estate, Audax Rd | Sun 10:00–16:00 |
| Oxfam Bookshop | Second-hand book shop | 69 Low Petergate | Mon–Sat 09:30–17:30 |
| Panda Mami York | Buffet restaurant | 19 Bridge St | Mon–Thu 12:00–15:00, 17:00–21:30 |
| Phone Doctor York | Mobile phone repair shop | 28 Parliament St | Mon–Sat 08:30–19:00 |
| Pictures By Rob | Photographer | 118 Middlecroft Dr | Daily Open 24 hours |
| Poetry Pharmacy | Book shop | 20 Coney St | Mon–Sat 09:00–18:00 |
| Pybus Newsagents | Newsagent | 25 High St | Mon–Sat 04:30–18:00 |
| Rainbow Restoration - York & Yorkshire Coast | Water damage restoration service | Unit 8, London Ebor Business Park, Millfield Ln | Daily Open 24 hours |
| Raspberry Photo Booth | Party equipment rental service | Nevis Way | Daily Open 24 hours |
| Rawcliffe Bar Park and Ride | Park and ride | Shipton Rd | Mon–Sat 05:30–23:00 |
| Redemption House, York | Gospel church | Northfield Lane | Mon–Tue 10:00–17:00 |
| Replay | Factory outlet shop | Unit 46, 35 St Nicholas Ave | Mon–Sat 09:30–20:00 |
| Rievaulx Abbey | Abbaye | Rievaulx Bank | Daily 10:00–17:00 |
| Rohan | Outdoor clothing and equipment shop | 35A Stonegate | Mon–Sat 09:00–17:00 |
| Samsonite Store | Luggage shop | Unit 74, Designer Outlet York, St Nicholas Ave | Mon–Fri 09:30–20:00 |
| Sandhouse Floor Sanding & Refinishing | Floor sanding and polishing service | 82 Millfield Ln | Daily 07:00–23:00 |
| Sarah Wilson Natural Therapies | Reiki therapist | Newton Way | Mon 11:00–18:00 |
| SCOTT-LOCK Auto locksmith | Locksmith | 75 Beech Ave | Daily Open 24 hours |
| Scrap My Car York | Motor vehicle dealer | 11 Kempton Cl | Daily Open 24 hours |
| Sewcialising | Fabric shop | 1 Coffee Yard | Mon–Sat 10:00–17:00 |
| Silk Heart Soaps | Novelty shop | Cornlands Road | Daily 09:00–05:00 |
| Skelton Parish Council | Parish | 1 Brecksfield | Daily 10:00–16:00 |
| Snowball Entertainments | Mobile disco service | 38 Rockingham Ave | Daily Open 24 hours |
| Sore Thumb Retro Games | Video game shop | 7 Gillygate | Sun 11:00–15:00 |
| SPARK York | Food court | 17-21 Piccadilly | Tue–Thu 08:00–22:30 |
| Spice Village | Indian takeaway | 18 The Village | Daily 17:00–22:00 |
| Squires Holistic Ltd | Holistic medicine practitioner | White Rose Cl | Daily Open 24 hours |
| St Andrew Place - Anchor | Housing association | St Andrew Pl | Daily Open 24 hours |