| China Red | Chinese restaurant | 76 Mersey St | Mon–Tue 16:00–23:00 |
| Cjl Flatpack Assembly | Handyman/Handywoman/Handyperson | St Mawgan Ct | Daily Open 24 hours |
| Community Recycling Centre | Household waste recycling centre | Sandy Ln | Daily 10:00–16:00 |
| craftsuprint ltd | Arts and crafts shop | Unit 27, Burtonwood Industrial Centre | Daily 09:00–17:00 |
| Croft Golf Centre | Golf driving range | Cross Ln | Sun 10:30–17:00 |
| Croft Village Memorial Hall | Village hall | 5 Mustard Ln | Mon–Thu 08:00–22:00 |
| Culcheth Christian Fellowship | Church | 85 Hob Hey Ln | Thu 19:00–20:30 |
| Culcheth Linear Park | Park and garden | 88 Wigshaw Ln | Daily Open 24 hours |
| Danny’s barbers | Barber shop | 446 Warrington Rd | Mon–Sat 08:30–18:00 |
| Dante Group | Air conditioning system supplier | 212 Europa Blvd | Daily Open 24 hours |
| Daresbury Laboratory | Laboratory | Keckwick Ln | Daily 08:00–19:00 |
| Dark Side Of The Spoon | Dessert restaurant | 2 Time Square, Market, Unit 35 Academy Way | Mon–Thu 09:00–17:00 |
| Darryl C Price | Water damage restoration service | 98 Delery Dr | Daily Open 24 hours |
| Dave Pluck | Off track betting shop | Fearnhead cross, Insall Rd | Mon–Fri 09:30–21:30 |
| Direct Garden Structures | Garden building supplier | Farm Alder Root Ln | Daily 09:00–17:00 |
| Dog & Partridge | Pub | Manchester Rd | Daily 12:00–23:00 |
| Dorado Lounge | Breakfast restaurant | 19 Market Place | Mon–Thu 09:00–22:00 |
| Drain Unblocking Warrington | Drainage service | 1st Floor, Rutherford House, Warrington Rd | Daily Open 24 hours |
| Drill Direct Ltd | Drilling contractor | Greys Court, 19, Kingsland Grange | Mon–Fri 06:00–17:30 |
| Drink Dash Ltd | Beer shop | Unit G1B6, Norman St | Tue–Thu 21:00–04:59 |
| DT Electrical - Electrician in Warrington | Electrician | 18 Coleport Cl | Daily 09:00–17:00 |
| East Orient | Buffet restaurant | 54 Horsemarket St | Mon 12:00–15:00, 17:00–21:00 |
| Eddie Stobart | Trucking company | Stretton Green Distribution Park, Langford Way | Mon Open 24 hours |
| Entec Doors Services ltd | Door supplier | Aston Court, Unit 17 & 18, Kingsland Grange | Daily Open 24 hours |
| F&F Clothing | Baby shop | Winwick Rd | Mon–Sat 06:00–00:00 |
| FAME Creative Talent | Performing arts group | 28 - 32 Milner St | Mon–Thu 16:00–21:00 |
| Fight Equipment UK | Martial arts supply shop | Unit 6, Priestley Business Centre, Priestley St | Mon–Fri 09:00–17:00 |
| Frostbite Refrigeration LTD | Trailer rental service | 15 Isherwood Cl | Daily Open 24 hours |
| FuelHub | Meal delivery | Europa Blvd | Daily Open 24 hours |
| Giggles Play Mill | Children's amusement centre | 3rd Floor, Evans House, Norman St | Mon–Fri 10:00–17:00 |