| Rancho Steak House | South American restaurant | 244A Morrison St | Mon–Thu 15:30–22:30 |
| Razzo Pizza Napoletana | Neapolitan restaurant | 59 Great Jct St | Mon–Thu 12:00–21:30 |
| Real Foods | Health food store | 37 Broughton St | Mon–Fri 09:00–19:00 |
| Rhubarb at Prestonfield House | Fine dining -ravintola | Priestfield Rd | Mon 12:00–22:00 |
| RJSL Designs | Valeting service | 53 Peffer Pl | Daily Open 24 hours |
| Royal Edinburgh Hospital | Psychiatric hospital | Morningside Pl | Daily Open 24 hours |
| Royal Infirmary of Edinburgh | General hospital | 15 Little France Cres | Daily Open 24 hours |
| Ryrie’s Bar | Restaurant | Edinburgh EH12 5EY | Mon–Thu 11:00–23:00 |
| Sanpo Yoshi 三宝食品店 | Asian grocery shop | 3 Holyrood Rd | Daily 12:00–20:00 |
| Saughton Rose Gardens | Garden | Balgreen Rd | Daily 09:00–21:00 |
| Saughton Sports Complex | Sports complex | Stevenson Dr | Mon–Thu 15:30–22:00 |
| Scottish Government | State government office | 3 E, St Andrew's House, 2 Regent Rd | Daily 08:00–22:00 |
| Scottish Rugby Store - Scottish Gas Murrayfield Stadium | Sportswear shop | Murrayfield Stadium, Roseburn St | Mon–Sat 09:00–17:00 |
| Sew Gallus | Stitching class | Riverside House, 502 Gorgie Rd | Daily 10:00–21:00 |
| Shahi Grill Indian Restaurant | Indian restaurant | 535 Lanark Rd | Mon–Thu 16:00–22:30 |
| Sip & Scoop Desserts Edinburgh | Dessert restaurant | 47 Great Jct St | Mon–Tue 14:00–23:00 |
| Sofia's Lounge | Lebanese restaurant | 166 Fountainbridge | Daily 12:30–21:30 |
| Soul Sushi | Sushi restaurant | 126 Nicolson St | Mon–Sat 12:00–21:00 |
| St Anthony's Chapel Ruins | Historical landmark | Holyrood Park, Queen's Dr | Daily Open 24 hours |
| St Giles' Cathedral | Katedraali | High St | Mon–Fri 10:00–18:00 |
| St John's Episcopal Church | Church of england church | St John's Church, Princes St. | Mon–Sat 10:00–16:00 |
| St Mary's Catholic Cathedral | Catholic cathedral | 61 York Pl | Mon–Fri 08:30–18:30 |
| St Mary's Episcopal Cathedral | Cathedral | Palmerston Pl | Mon–Fri 08:00–18:00 |
| Stewart and Co Defence | Criminal defence lawyer | Office 43, 4-5 Lochside Way | Daily Open 24 hours |
| Street of Beijing | Chinese restaurant | 37 Home St | Mon–Tue 12:00–00:00 |
| Studio XIII Gallery | Tattoo shop | 3 Jeffrey St | Mon–Sat 10:00–18:00 |
| Surgeons' Hall Museum | Wissenschaftsmuseum | Surgeons Hall Museums, Nicolson St | Daily 10:00–17:00 |
| Synergy Surveying Limited | Asbestos testing service | 53 Frederick St | Daily 07:00–19:00 |
| Tartan Weaving Mill and Exhibition | Geschenkladen | 555 Castlehill | Daily 09:00–19:00 |
| The Ball Room Sports Bar (Meadowbank) - Pool, Snooker & Darts Hall | Snooker and pool club | 25 Jocks Lodge | Daily 12:00–00:00 |