| Discovery Church Wroughton | Gospel church | Discovery Church Wroughton, Markham Rd | Wed 14:00–16:00 |
| Divorce-Online | Family lawyer | Unit 3, The Meads Business Centre, Ashworth Rd | Mon–Thu 09:00–17:00 |
| Don Churro (Swindon) | Restaurant | 94A, Designer Outlet, Kemble Dr | Thu 10:00–20:00 |
| Down To Earth Landscape & Paving Specialists | Paving contractor | Down to Earth Landscaping & Paving supplies Greatfield Farm | Mon 09:00–17:00 |
| DP Building & Refurbishments | Building restoration service | 117 Montagu St | Mon–Fri 08:00–17:30 |
| DPDS Consulting Group | Property consultant | Old Bank House, 5 Devizes Rd | Mon 09:00–17:30 |
| Draft2craft | Interior designer | 49A Grosvenor Rd | Mon–Fri Open 24 hours |
| Dubai Restaurant & Shisha Lounge (Swindon) | Persian restaurant | 96 Manchester Rd | Mon 12:00–22:00 |
| Dynamic Cleaning Services Ltd | House cleaning service | 3, 28 St Philip's Rd | Daily 09:00–17:00 |
| E - Brows, Permanent Make Up | Permanent make-up clinic | 43 Silchester Way | Mon 09:00–18:00 |
| Eastcott Studios | Art studio | 28 Eastcott Hill | Mon 18:30–20:30 |
| Easy Financial Services | Financial advisor | EASY FINANCIAL SERVICES, 140 a High St | Mon–Tue 09:00–17:00 |
| Edmont | Joiner | Hyde Rd | Mon–Fri 09:00–17:00 |
| Elena Prousskaia Cosmetic Surgery Swindon | Plastic surgeon | BMI The Ridgeway Hospital, Moormead Rd | Mon–Fri 09:00–17:30 |
| Elite Tyre Rescue | Tire service | Salzgitter Dr, Standen Way | Daily Open 24 hours |
| Enlan Ltd | Property maintenance | Leaze Barn, Hook St | Mon–Fri 08:00–17:00 |
| Enterprise Works Timber & Fencing | Timber merchant | Unit 1a, 1b Gipsy Ln | Mon–Thu 08:00–16:00 |
| Equinox Building Solutions (Swindon) Ltd | Property maintenance | Unit 2a Bagbury Park, The St | Mon–Fri 08:00–16:30 |
| Equinox Glass & Glazing | Window supplier | Unit 2a Bagbury Park, The Street, Lydiard Millicent | Mon–Fri 08:30–16:30 |
| Equippers Church Swindon | Church | Trinity Hall, Victoria Rd | Mon 09:00–17:00, 18:00–21:00 |
| Every Cloud | Non-profit organisation | Stanton Farmhouse, Stanton Country Park | Sat–Sun 10:00–15:00 |
| Evolution Car Center LTD | Car painting | 5, Aspen Close, Kembrey Bussines Park | Mon–Thu 08:00–18:00 |
| Evolve Litho | Commercial printer | Unit 103, Rivermead Business Centre, 54 Rivermead Dr | Mon–Fri 08:00–17:00 |
| Fairytale Occasions | Bridal shop | 1, Barton Court, 11-12 High St | Tue–Wed 09:00–14:00 |
| First Agency Direct Ltd | Temp agency | 1, Ellis Barn | Mon–Fri 06:00–20:00 |
| Fixed Locally | Second-hand computer shop | 35 Westrop | Mon 07:00–19:00 |
| Frasers Plus Designer Outlet Swindon | Shopping outlet | Kemble Dr | Mon–Sat 10:00–20:00 |
| FSR Security Ltd | Security system supplier | 7 Waggoner Cl | Daily Open 24 hours |
| Garden Of Eden Cane | Tienda de mobiliario de caña | 200 Murdock Rd | Mon–Fri 09:00–18:00 |
| George Clothing | Clothing shop | 15-17, West Swindon District Centre | Mon–Sat 09:00–17:30 |