| BioViron Iternational | Packaging supply shop | Bowman House Business Centre, Whitehill Ln | Mon–Fri Open 24 hours |
| Bison Motorhomes | Campervan and caravan rental agency | 17 Bouverie Ave | Daily Open 24 hours |
| Blackberry Cleaning & Support Services Ltd | Cleaning service | Anchor Business Centre | Mon Open 24 hours |
| BlockBlueLight UK - Blue Light Glasses & Lighting | Optician | Unit 6, Westerngate, Langley Rd | Daily Open 24 hours |
| Blue Line Sports Ltd | Sporting goods shop | Unit 18, Hope Well House, Whitehill Ln | Mon–Fri 09:00–17:00 |
| Blue Sky Fostering West Country | Foster care service | Unit 25, Borough Fields Shopping Centre | Mon–Fri 09:00–17:00 |
| Blunsdon Pre-School Ltd | Educational institution | High St | Mon–Thu 08:30–15:00 |
| BookCheck Swindon | Bookkeeping service | Regus House, Windmill Hill Business Park, Whitehill Way | Mon–Fri Open 24 hours |
| Booth & Son Ltd | Steel fabricator | Purton Industrial Estate, Mopes Ln | Mon–Tue 08:00–16:30 |
| Box and Seal | Warehouse | Whitehill Industrial Park, Whitehill Ln | Mon–Fri 09:00–17:00 |
| Brand Promo and Merch | Clothing supplier | Pembroke Centre, Unit 11 Flexspace, Cheney Manor Industrial Est | Mon–Thu 09:00–17:00 |
| Broad Town Cars Ltd | Motor vehicle dealer | Broad Town, Royal Wootton Bassett, Swindon SN4 7RB | Mon 08:30–17:30 |
| Brunel Office Supplies Ltd | Office supplies shop | Ste 46, The Shaftesbury Centre, Percy St | Thu–Fri 09:00–18:00 |
| BumbleB Services | Window cleaning service | Heytsbury Gardens | Mon 08:00–20:00 |
| Bupa Dental Care Highworth | Dentist | 11 Sheep St | Mon 08:30–18:00 |
| Burden Electronics | Electronics retail and repair shop | 160 County Road, Opposite Swindon Town FC, near The Magic Roundabout | Mon–Tue 09:00–18:00 |
| Burger and Mexican Now (Swindon) | Hamburger restaurant | 188-189 Victoria Rd | Thu 16:00–22:00 |
| Butterfly World & Farm Park | Zoo | Hay Ln | Mon–Sat 10:00–17:00 |
| C & T Electronics Ltd. | Appraiser | 5 Greenwich Cl | Mon–Fri Open 24 hours |
| Cadillac Plastic Ltd | Plastic fabrication company | Unit 1 Rivermead Dr | Mon–Thu 08:45–17:00 |
| Caffini (Havelock Street) | Pizza restaurant | Town, 29 Havelock St | Mon 08:30–17:00 |
| Cameo Glass Ltd | Glass merchant | 100 Faraday Park | Mon–Fri 08:00–17:00 |
| Caravan Accessories 4U | Caravan supply shop | Swindon Caravan Centre, Caravan & Motorhome Centre, Greatfield, Royal Wootton Bassett | Mon–Sat 09:00–17:30 |
| Care green tree services | Tree service | Calcutt, Swindon SN6 6JR | Daily Open 24 hours |
| Carpet Warehouse Swindon Ltd | Carpet retail shop | 86 Beatrice St | Mon–Sat 10:00–17:00 |
| Catalent Pharma Solutions | Pharmaceutical company | Frankland Rd | Mon–Fri 08:00–16:00 |
| Centra Heating, Plumbing & Drainage Ltd | HVAC contractor | 20 Cartwright Dr | Daily Open 24 hours |
| Channon Property Maintenance | Fence contractor | 57 Thorne Rd | Mon 07:30–19:30 |
| Chayil Couture | Dressmaker | 5 Barcote Cl | Mon–Sat 09:00–18:00 |
| Chelsea Home & Leisure Ltd. | Garden furniture shop | unit 6, Bridge paddocks, Braydon Rd | Mon–Tue Open 24 hours |