| Delta Fibreglass Solutions Ltd | Fibreglass repair service | Newby Road Industrial Estate, Newby Rd | Mon–Fri 08:00–17:00 |
| Delta Power Services | Marine broker | Newby Road Industrial Estate, Newby Rd | Mon–Fri 08:30–17:00 |
| Design & Print | Consultant | Design & Print, Dale House, Tiviot Dl | Fri 08:00–16:00 |
| Design Haus Partnership Ltd | Architectural designer | Elizabeth House, 486 Didsbury Rd | Mon–Fri 09:00–17:00 |
| Dial House Medical Centre | Medical centre | 131 Mile End Ln | Mon–Tue 08:00–18:30 |
| Digital Marketing Agency Stockport | Internet marketing service | 9 Park Rd | Fri 09:00–18:00 |
| Direct Packaging Solutions Ltd | Packaging supply shop | Grove Works, Ind Est, Battersea Rd | Thu 08:30–16:30 |
| Direct Stoves | Tienda de estufas de leña | 137 Wellington Rd N | Mon–Fri 09:00–17:00 |
| Directplumb2u | Plumbers' merchant | Unit 11, Longfield Farm, Hall Moss Ln | Daily Open 24 hours |
| Dirt Factory Bike Shop | Bicycle shop | Cote Green Rd | Wed–Fri 11:00–19:00 |
| Discount washers | Appliance shop | 36 Gorton Rd | Thu 09:00–17:00 |
| DMK Properties | Student accommodation centre | Unit 3, Boundary Court, Crossley Rd | Mon 09:00–16:00 |
| Domestic Air Conditioning | Air conditioning contractor | house, 1 levens road Copyrite | Mon–Wed 07:00–18:30 |
| Dragon Palace Chinese Restaurant | Chinese restaurant | 26-28 Gorton Rd | Tue–Thu 17:00–23:00 |
| DRG Health Clinic | Pain control clinic | 16-18 London Rd | Fri 10:00–15:30 |
| DRW Groundworks & Landscaping Ltd | Excavating contractor | 22 Pear Tree Cl | Daily 06:30–18:00 |
| Dutsons | Deli | 22-24 Town St | Mon–Sat 08:30–17:00 |
| Duttons Bramhall | Restaurant | Duttons Bramhall, Ack Ln E | Mon–Thu 11:00–23:00 |
| DW Landscaping Solutions | Landscaper | 57 Houldsworth St | Daily 08:30–17:00 |
| Eagle Glass - glass suppliers to trade and public | Glass shop | Unit 18 Portwood Trading Estate | Mon–Wed 08:30–16:30 |
| Easy Access Self Storage (Stockport) | Self storage facility | Easy Access Units, Oldmoor Rd | Mon–Fri 08:30–17:30 |
| Echo Hearing Bramhall | Hearing aid shop | 30a Bramhall Ln S | Tue 09:15–17:30 |
| Eco-Pulito Clean Ltd | Janitorial service | Labyrinth House Bussiness Center, 43 Middle Hillgate | Daily 09:00–18:00 |
| Eden Bar & Eatery | Cocktail bar | 54 Heaton Moor Rd | Thu 12:00–22:30 |
| Edgeley Pharmacy | Medical supply store | 99 Bloom St | Mon–Fri 09:00–18:00 |
| Edina UK Ltd (Manchester) | Diesel engine repair service | Units 6, 12 and 13, Rugby Park, Bletchley Rd | Mon–Thu 08:30–17:00 |
| Egan Reid Group | Office equipment supplier | Unit 5, Grosvenor Business Park, 5 Horsfield Way | Fri 08:30–17:30 |
| Elegant tailors | Clothing alteration service | 100 Princes St | Mon–Tue 09:00–17:30 |
| Elm Cottage Day Nursery, Crescent Park | Pre-school | 11 Crescent Park | Mon–Fri 08:00–18:00 |
| Elwers Ltd | Golf instructor | Golf Club, Marple Golf Club Ltd, Barnsfold Rd | Mon–Fri 08:00–18:00 |