| DrBK Clinic Reading | Zahnästhetische praxis | 115 Queens Rd | Thu 09:00–18:00 |
| Dream Dresses Prom & party | Dress shop | Opposite IMO cash wash, Honey End Ln | Tue–Sat 09:15–18:00 |
| Dry Ice Nationwide Limited | Dry ice supplier | Unit 9 Manor Farm Rd | Mon–Fri 09:00–17:00 |
| Dua Lounge | Shisha bar | 355 Oxford Rd | Daily 15:00–00:00 |
| Ealum Ltd | Double glazing installer | 40 Caversham Rd | Mon–Sat 09:00–17:00 |
| Earley Acupuncture Clinic | Acupuncture clinic | 43 Andrews Rd | Tue 16:00–19:00 |
| Easy Concrete Services Ltd | Concrete product supplier | Units 1 & 2, Woodstock, Paices Hill | Mon–Fri 07:00–17:00 |
| Eden Mazda Reading | Mazda dealer | Rose Kiln Ln | Mon 08:30–18:00 |
| EL plumbing and heating 24/7 Emergency. | Sanitärinstallateur | 18 Grasmere Ave | Thu Open 24 hours |
| Elite Auto Ltd - House of Luxury Car Accessories - Land Rover, Tesla, Ford, Lamborghini, Porsche | Car accessories shop | Unit B2, Lambs Farm Business Park, Basingstoke Rd | Mon–Fri 09:00–17:00 |
| Elmdale Maintenance Ltd | Office equipment supplier | 4 & 5, Bacchus House | Mon–Fri 08:30–18:00 |
| Englefield Stores & Tea Room | Tea room | The Street | Mon–Sat 10:00–15:00 |
| English Village Designs | Model design company | The New House, Wokingham Rd | Mon 09:30–17:00 |
| Envirogreen Ltd | Chemical recycling and disposal service | Pitchkettle Farm, Goodboy's Ln | Fri 08:00–18:00 |
| Ephesus Grill | Kebabimbiss | Whitley St | Daily 12:00–00:00 |
| Esquires Coffee Reading | Coffee shop | 8 Flagstaff Rd | Mon–Fri 07:00–18:00 |
| Et Lorem Ltd Head Office | Kitchen renovator | 100 Berkshire Pl | Mon–Fri 09:00–17:00 |
| Evadigix Ltd | Security system installation service | East St | Mon–Sat 08:00–17:00 |
| Evolve Outdoors Ltd | Carport and pergola builder | 10 Beech Ct, Wokingham Rd | Mon–Fri 09:00–17:00 |
| Ewbank Psychotherapy | Psychotherapist | Waterside Dr | Mon–Wed 09:00–18:00 |
| Feat of Clay Baby Prints | Pottery shop | 1 Rochester Ave | Mon–Fri 09:00–17:00 |
| Festival Outlet | Festival | 19 Master Cl | Daily 10:00–16:00 |
| Field Seymour Parkes LLP | Rechtsanwalt | 1 London St | Thu 08:30–17:30 |
| Fiona-Jane Morley | Massage therapist | 1 Addington Gardens | Sun 10:00–12:00 |
| First Friday Club | Geschäftszentrum | 2 Bridge St | Daily 06:00–22:30 |
| First Stop Home Improvements Ltd | Unternehmen für isolationsarbeiten | Unit 3, Thames Court, Richfield Ave | Mon–Fri 08:00–18:00 |
| Flat-Out Burgers by Taster | Meal delivery | 166 Oxford Rd | Mon 16:00–03:00 |
| Focal Point Advertising | Advertising agency | Lambwood Hill | Mon–Fri 09:00–17:30 |
| Fora - Thames Tower | Büroflächenvermietung | Thames Tower, Station Rd | Mon 08:30–18:00 |
| Forest Oak Construction | Wohnungsbauunternehmen | 14 Three Firs Way | Thu 08:00–17:00 |