| Eagles Jerk & Grill | Caribbean restaurant | 6 Harrier Ct, High Trees | Mon–Thu 12:00–21:00 |
| EarthGrit | Health food shop | Whitehouse, Milton Keynes MK8 1BE | Daily Open 24 hours |
| Eastern Paradise | Indian restaurant | 10, 12 Wolverton Rd | Mon 17:00–23:00 |
| Eating Greek MK | Greek restaurant | 8 Church St | Mon 12:00–22:00 |
| EFD Corporate Ltd | Work clothes shop | 8 Centurion Ct, Brick Cl | Mon–Fri 08:30–17:00 |
| Egg o’clock Japanese Street Food Milton Keynes | Japanese curry restaurant | Towergate | Thu 12:00–19:30 |
| EJ Antiques | Antique shop | 22 Buckingham St | Daily 09:00–22:00 |
| Electron-X Ltd | X-ray equipment supplier | 5 Thornton Chase | Mon–Fri 09:00–17:00 |
| Elegancy Blinds Ltd | Blinds shop | 8 The, Stacey Bushes Trading Centre, Erica Rd | Mon 08:00–16:30 |
| Eles Fashion | Designer clothing shop | 92 Farmborough | Mon–Sat 10:00–17:00 |
| Elite Window Cleaning | Window cleaning service | 81 Blackmoor Gate | Daily Open 24 hours |
| English Language House | English language school | 300 Saxon Gate | Mon–Fri 09:00–17:00 |
| Enplan UK Ltd | Landscape architect | Gloucester House, 399 Silbury Blvd | Mon–Fri 09:00–17:30 |
| Enrich Beauty (MK) Ltd | Beauty salon | 7 Barkestone Cl | Mon–Sat 09:00–18:00 |
| Enveco Ltd | Manufacturer | 3, Eastlake Park, Opal Dr | Mon–Thu 09:00–17:30 |
| Evangelical Free Church Stony Stratford | Evangelical church | 11 Wolverton Rd | Daily 08:00–22:00 |
| Evergreen Foods | Butchers | 26 Penryn Ave | Daily 09:00–21:00 |
| Eximia Concept Uk | Beauty product supplier | 651 S Fifth St | Mon–Fri 09:00–18:30 |
| face2faceHR Milton Keynes, Sue Pardy | Human resource consulting | 16 Station Rd | Mon 09:00–17:00 |
| Faith Tabernacle United Pentecostal Church | Pentecostal church | 124 Newport Rd | Tue 11:00–13:00, 19:30–21:00 |
| Fall Protection Milton Keynes | Safety equipment supplier | 41 Underwood Pl | Mon–Fri 08:00–17:00 |
| Fastfit Station MK Ltd | MOT centre | Unit 4, Cannons Industrial Park, Dean's Rd | Mon–Fri 08:00–17:30 |
| Feather & Black Milton Keynes | Bedroom furniture store | Routeco Retail Park, Snowdon Dr | Mon–Fri 10:00–20:00 |
| Feel Good Steps | Foot care | 74 Whiteley Cres | Mon–Tue 09:00–18:00 |
| Fenster Glazing - Windows & Doors Showroom | Double glazing installer | 98 Alston Dr | Mon–Fri 08:30–17:00 |
| Finesse Casinos | Party equipment rental service | 3 Camomile Ct | Mon–Fri 09:30–17:00 |
| Fireaway Pizza Milton Keynes | Pizza restaurant | 16B Garrick Walk, 12th Street | Mon–Thu 12:00–02:00 |
| FireStop Technologies Ltd. | Fire protection consultant | 16 Chetwode Ave | Mon–Fri 09:00–17:00 |
| First Avenue Supplies Ltd | Embroidery service | 12 James Way | Mon–Fri 08:00–18:00 |
| Fleming Medical UK Ltd. | Medical equipment supplier | Luminous House, 300 S Row | Mon–Fri 09:00–17:00 |