| Drive Hyundai York | Hyundai dealer | Drive Hyundai, Great N Way | Mon–Fri 08:30–18:00 |
| Edmund Optics | Optical products manufacturer | 1 Opus Ave | Mon–Fri 08:00–17:00 |
| Hemblade Acupuncture | Acupuncturist | Independence House, Millfield Ln | Wed–Thu 09:00–18:00 |
| Limetree House | Nursing home | Main St | Daily Open 24 hours |
| My Mobile PT | Personal trainer | York Business Park, Unit 24 Rose Ave | Mon–Thu 08:00–20:00 |
| OH One - Occupational Health (York) | Occupational health service | Millfield Lane, Head Office Independance | Mon–Fri 09:00–17:00 |
| Plumbcore | Gas installation service | Workshop 3, Oakwood Farm, Northfield Lane | Mon–Tue 08:00–16:30 |
| Poppleton Centre | Community centre | Main St | Mon 08:30–21:00 |
| Rainbow Restoration - York & Yorkshire Coast | Water damage restoration service | Unit 8, London Ebor Business Park, Millfield Ln | Daily Open 24 hours |
| Regen Physio York North - Poppleton | Physiotherapist | Unit 1A, Bannatyne Health Club & Spa, The Millfield, York Business Park | Thu–Fri 08:00–21:00 |
| Sandhouse Floor Sanding & Refinishing | Floor sanding and polishing service | 82 Millfield Ln | Daily 07:00–23:00 |
| Saville Group | Audio visual consultant | Millfield Lane | Mon–Fri 08:30–17:30 |
| The Blue Butterfly York | Reiki therapist | 19 Millfield Ln | Mon–Fri 09:00–17:00 |
| Webhosting UK Com Ltd | Web hosting company | Regency House, York Business Park | Daily Open 24 hours |
| York Coffee Emporium | Coffee roastery | 4-5, Rose Centre Business Park, Rose Ave | Mon–Fri 08:30–17:00 |
| Bannatyne Health Club And Spa York | Fitness centre | Unit 1A, The Millfield, York Business Park, White Rose Cl | Thu–Fri 06:00–22:00 |
| Bradshaws Of York | Caterer | Unit 3, London Ebor Business Park, Millfield Ln | Mon–Fri 09:00–16:00 |
| Chokdee Martial Fitness Academy | Martial arts school | York Business Park, Unit 24 Rose Ave | Mon 17:00–21:00 |
| Croft Residential | Estate agent | House, Office, Independence, 2 Millfield Ln | Mon–Fri 08:30–20:00 |
| Poppleton Village Butchers | Butchers | 22 Allerton Dr | Tue 08:00–15:00 |
| PPH Commercial | Commercial agent | Independence House, Millfield Ln | Mon–Fri 09:00–17:30 |
| Westminster Business Centre | Business centre | York Business Park, 10 Great N Way | Thu–Fri 07:00–22:00 |
| Westminster Place | Office rental agency | York Business Park, Great N Way | Mon–Tue 08:30–17:00 |
| York Kitchens & Interiors | Kitchen, Bathroom & Bedroom Showroom | Bathroom renovator | 21 Rose Ave | Thu 09:00–17:00 |
| Yorvik Windscreens Ltd | Glass repair service | York Business Park, Unit 23 Rose Ave | Mon 08:00–17:00 |
| Popolo Ceramico North Yorkshire | Ceramic manufacturer | Unit 3, York Business Park, Rose Ave | — |