| Marple Con Club | Bar | 119 Church Ln | Mon 12:00–23:00 |
| Psychi | Sports accessories wholesaler | Shepley Industrial Estate, Units 2+3 Pennine View Estate, Shepley Ln | — |
| The E-Cig Store Marple | Vaporiser shop | 35 Stockport Rd | Mon–Sat 08:30–17:30 |
| Absolute Care and Support (UK) Limited | Home care service | Suite 9, First Floor, Marple House, 39 Stockport Rd | Mon–Fri 09:00–17:00 |
| Altertherm Air Conditioning Ltd | Air conditioning system supplier | Brickbridge Rd | Mon–Tue 09:00–17:00 |
| Arden Software | Software company | Arden House, 1 Shepley Ln | Daily Open 24 hours |
| Boujee Bliss Events | Event planning service | 42 Market St | Fri 09:00–17:00 |
| Hawk Green Reading Room | Village hall | Upper Hibbert Lane, Marple, Upper Hibbert Ln | Mon 08:30–23:00 |
| Kay Construction (Marple) Ltd | General contractor | 44 Stockport Rd | Mon–Fri 07:00–17:30 |
| Lentils and Lather | General store | 107 Stockport Rd | Tue 09:00–17:00 |
| Manchester Canoe Club | Canoe and kayak club | Lower, Dale Rd | Mon 18:00–20:00 |
| Marple Cottage Surgery | Medical group | Marple Cottage Surgery, 50 Church St | Mon 08:00–20:00 |
| Mrs Chips | Fish and chips takeaway | 3 Derby St | Mon 16:00–20:00 |
| Nathan The Chimney Sweep | Chimney sweep | Slack hall farm, Turf Lea Rd | Mon–Wed 09:00–18:30 |
| Nitrotek Limited | Model shop | Goyt Mill, Upper Hibbert Ln | Thu–Fri 10:00–18:00 |
| Pearson concrete Ltd | Ready-mix concrete supplier | Pearson Concrete Ltd, Railway Rd | Mon–Sat 08:00–16:30 |
| Prophecy Cricket | Cricket shop | 41 Market St | Fri 10:30–16:30 |
| Sarma Marple | Turkish restaurant | 95 Stockport Rd | Mon–Sat 14:00–22:00 |
| The London Candle Company (Cash & Carry Warehouse) | Cash and carry wholesaler | Unit I, Goyt Mill, Upper Hibbert Ln | Mon–Fri 08:30–15:00 |
| Barchester - Arbour Court Care Home | Nursing home | Buxton Ln | Sun Open 24 hours |
| Benjis Pet Food and Accessories | Pet food and animal feeds | 44 Market St | Mon–Sat 09:00–16:00 |
| Dig Inn | Record shop | 72 Stockport Rd | Sat 11:00–23:00 |
| Doro Italiano Restaurant & Bar | Italian restaurant | 103 Church Ln | Mon–Sat 12:00–22:00 |
| JWAuto Electrics | Auto electrical service | 20 Woodville Dr | — |