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American restaurants in Southampton
Southampton has 5 American restaurants in our directory. Many are around Milbrook and Totton. Most open at 06:00 and close at 00:00 on weekdays.
5 places Checked October 2026
| Name | Category | Address | Opening times |
|---|---|---|---|
| McDonald's | Fast food restaurant | Green Park Rd | Daily 06:00–00:00 |
| McDonald's | American restaurant | 97 Commercial Rd | Daily 06:00–00:00 |
| McDonald's | American restaurant | Roadchef Rownhams Services, Westbound, M27 | Daily Open 24 hours |
| Ed's Easy Diner | Diner | Unit R4, westquay, Portland Terrace | Thu 10:00–20:00 |
| 7Bone Burger Co. Southampton | Hamburger restaurant | 29 Bedford Pl | Thu 12:00–21:30 |