| A1 Pallets & Timber Products Ltd | Packaging company | Brooke Building, Shepcote Ln | Mon–Fri 08:00–16:30 |
| Ancient Wisdom - Giftware Wholesale | Wholesaler | Europa Drive Affinity, Park | Mon–Fri 08:00–16:00 |
| Arthrex | Medical technology manufacturer | Unit 1, Bessemer Park, Shepcote Ln | Mon–Fri 07:30–17:30 |
| Blackburn Meadows Power Station | Power station | 12 A631 | Daily Open 24 hours |
| Engineerable UK | Tool manufacturer | Park House Lane, sher-inghs house | Mon–Fri 08:00–16:30 |
| Go Big Driving School Ltd. | Driving school | Ancient Wisdom, Europa Dr | Mon–Fri 08:00–16:30 |
| Little Stars 4D Scan Sheffield | Medical diagnostic imaging centre | Unit 6, Shepcote Office Village | Mon 12:00–20:00 |
| MB Advertising & Marketing Ltd | Advertising agency | MB House, 248 Shepcote Ln | Fri 09:00–17:30 |
| Micro Precision (Yorkshire) Ltd | Measuring instruments supplier | Unit 3, Shepcote Enterprise Park 2, 3 Europa Dr | Mon–Thu 07:30–15:45 |
| Noah's Ark Creations | Rustic furniture shop | Brooke Building, Shepcote Ln | Mon–Tue 10:00–16:00 |
| South Yorkshire Firewood | Firewood supplier | Legacy House, Greasbro Rd | Mon–Fri 08:00–17:00 |
| Tyzack Machine Knives | Manufacturer | 335 Shepcote Ln | Mon–Thu 08:00–16:00 |
| Hancocks | Confectionery wholesaler | Park House Ln | Mon 08:00–16:00 |
| IKEA Sheffield | Home furniture shop | Sheffield Rd | Mon–Sat 10:00–21:00 |
| JCT600 Volkswagen Van Centre Sheffield | Volkswagen dealer | 2 Europa Cl | Mon–Fri 08:30–18:00 |
| Mamas & Papas Meadowhall (At Next Home) | Baby shop | CH6R+6W, Vulcan Rd | Mon–Fri 09:30–21:00 |
| MAN Truck & Bus Sheffield | Truck repair shop | Shepcote Ln | Thu 06:00–22:30 |
| Motorpoint Sheffield | Used truck dealer | Europa Link | Thu 10:00–20:00 |
| ADM Windows Ltd | PVC windows supplier | Unit 13, Shepcote Ln | Mon 08:30–16:30 |
| Apollo Fuels Ltd | Oil and gas exploration service | Templeborough Works, Sheffield Rd | Mon 07:00–04:30 |
| Crown Kids Parties- Face Painter | Artist | Tinsley Roundabout | Mon 09:00–21:00 |
| Football Trophy Shop | Trophy shop | 34 Maplebeck Dr | Mon–Fri 07:00–19:00 |
| Fulcrum | Utilities contractor | Sheffield Business Park, 4 Europa Ct | Fri 08:30–16:30 |
| GA Furnace Engineering Ltd | Engineer | Unit 6, Junction 34 Industrial Estate, Greasbro Rd | Mon 07:00–16:00 |
| MM Bell & Sons | Packaging supply shop | Shepcote Enterprise Park 2, Units 4-6, 3 Europa Dr | Mon–Fri 08:00–16:30 |
| Sports Trophy Co | Tienda de trofeos | 34 Maplebeck Dr | Mon 07:00–21:00 |
| The Fan Cave Memorabilia | Tienda de artículos deportivos coleccionables | Unit 1, Shepcote Enterprise Park, 1 1 Europa Dr | Mon–Fri 09:00–17:00 |
| Blue Chip PFP | Fire protection service | Unit 5, Shepcote Office Village, Shepcote Ln | — |
| CHEC Sheffield | Ophthalmology clinic | Workstation, Unit 12 Europa View | Mon 07:30–17:30 |
| PRL Logistics Ltd | Warehouse | Shepcote House, 5 Shepcote Ln | — |